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Biopharmaceutical research company specializing in cannabis- and plant-inspired medicines shares strategic plan for 2023 and key developments from 2022
LAS VEGAS, March 7, 2023 (Newswire.com)
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Gb Sciences, Inc. (OTCQB:GBLX), a leading cannabis- and plant-inspired biopharmaceutical research and development company, issued a letter to shareholders today from President, Chief Science Officer, and Director Dr. Andrea Small-Howard and Chairman and CEO John Poss summarizing key developments from 2022 and providing strategic plans for 2023. Full text of the shareholder letter follows.
A MESSAGE FROM BOTH THE PRESIDENT AND THE CHAIRMAN OF GB SCIENCES, INC.
To Our Shareholders:
In 2022, Gb Sciences achieved significant milestones advancing our plant-inspired drug development pipeline for the treatment of a broad spectrum of critical and prevalent diseases, which supports the value of PhAROS™, our proprietary AI-enabled Drug Discovery Platform. Gb Sciences is entering 2023 with very good reason for excitement and optimism for our shareholders and for the potential to develop first-in-class drugs to treat serious disorders such as: Parkinson’s Disease, Advanced Heart Disease, Chronic Pain, Inflammation, Anxiety and Depression. In addition, our intellectual property portfolio currently contains six issued U.S. and four issued foreign patents, as well as 15 U.S. and 49 foreign patent-pending applications that cover our novel AI-enabled drug discovery platform and proprietary therapies for more than 65 different disorders.
Recognizing the value of our PhAROS™ Drug Discovery Platform for expediting our novel plant-inspired drug pipeline, we also realize that PhAROS™ has the potential to be of high value to other drug development biotech and pharmaceutical companies. With its data analytics and machine learning capabilities providing a breakthrough in drug discovery, our PhAROS™ Drug Discovery Platform greatly reduces the time and money required to discover and bring novel formulations to market. Therefore, in addition to developing our own biopharma pipeline, we plan to monetize PhAROS™ by pursuing potential licensing and/or partnerships with other drug developers that offer the potential to generate substantial, recurring, high-margin revenues to Gb Sciences.
While other drug developers pursue conventional drug pathways, Gb Sciences is developing novel Minimal Essential Mixtures derived from the active ingredients found within traditional plant-based medicines that are still commonly used across the world. Traditional medicines that are mostly plant based have been used for centuries and are composed of all the ingredients for specific plants which can number in the hundreds or even thousands. Gb Sciences uses our novel PhAROS™ Drug Discovery Platform to determine which three ingredients of the hundreds of ingredients found in each plant are the most effective and with the fewest adverse side effects.
In 2022, Gb Sciences has successfully prepared our lead program in Parkinson’s disease for a first-in-human trial through the following essential steps: a) creating clinical prototypes by combining our proprietary Parkinson’s formulas with a convenient oral delivery system; b) performing a dose response study in rodents to establish the correct range of active ingredients for our first-in-human trial; c) performing necessary ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicology) tests on the clinical prototypes; and d) selecting a Contract Research Organization (CRO) to prepare an Investigational New Drug (IND) application to the U.S. FDA to begin our first-in-human trial.
Working with Catalent Pharma in 2022, Gb Sciences has successfully prepared the clinical prototypes of our proprietary cannabinoid-based formulations for Parkinson’s disease in Catalent Pharma’s proprietary Zydis® delivery system. Catalent Pharma’s Zydis® delivery system is an Orally Disintegrating Tablet format that should be ideal for delivering our cannabinoid-ratio controlled formulations to Parkinson’s patients. More than 50% of Parkinson’s patients have trouble swallowing, but the Zydis® format delivers the active ingredients into the mouth by dispersion without needing water or the ability to swallow.
In February of 2023, the University of Lethbridge has successfully completed our dose response study in rodents, which helps us to establish the correct dosing of our cannabinoid-containing Parkinson’s formulations in our first-in-human trial. The results of this important study will be delivered to Gb Sciences from the University of Lethbridge within the next six weeks.
Prior to filing our IND application for our first-in-human trial on our Parkinson’s formulations, Gb Sciences must conduct ADMET testing on the clinical prototypes being formulated for us by Catalent Pharma. Gb Sciences has selected Labcorp Drug Development, formerly Covance, to perform our IND-enabling studies due to their expertise and testing locations in the United Kingdom near to where the ODT tablets are being manufactured by Catalent Pharma.
In the IND application for our Parkinson’s disease therapeutics, the ADMET testing data from Labcorp will be combined with the Chemistry Manufacturing and Controls (CMC) data prepared by Catalent Pharma and our proof-of-concept data from the National Research Council (NRC) of Canada. In the near future, we expect to announce the selection of the Contract Research Organization that will write the IND application and run the first-in-human trials for our novel treatment for the motor symptoms of Parkinson’s disease.
Gb Sciences has four other promising late-preclinical stage programs, including our COVID-related cytokine release syndrome (COVID-CRS) formulations and our time-released oral nanoparticle formulations for chronic pain. We have achieved preclinical proof-of-concept for our COVID-CRS formulas in studies performed by Michigan State University. Our chronic pain formulations are being validated in animal trials at the National Research Council of Canada. Recently, we have announced that our kava-inspired formulas for anxiety have achieved animal proof-of-concept. Gb Sciences is now preparing its non-psychedelic, kava-based anxiety formulations to treat the growing global need for anxiety and depression relief.
In closing, we would like to thank those shareholders who have supported our company this year and in past years. Our goal remains to produce maximum shareholder value while also providing innovative new therapeutic options for patients that need them.
Sincerely,
Dr. Andrea Small-Howard
President, CSO & Director
Gb Sciences, Inc.
John Poss
Chairman & CEO
Gb Sciences, Inc.
To learn more about Gb Sciences, visit www.gbsciences.com.
About Gb Sciences and GbS Global Biopharma
Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented, disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary GbS Global Biopharma, Inc. The “plant-inspired” active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences’ intellectual property portfolio contains six issued U.S. and four issued foreign patents, as well as 15 U.S. and 49 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences’ lead program for Parkinson’s disease is being prepared for a first-in-human clinical trial. Gb Sciences’ formulations for chronic pain, anxiety and depression are currently in preclinical animal studies with researchers at the National Research Council of Canada (NRC). The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences’ productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com.
Forward-Looking Statements
This press release may contain statements relating to future results or events, which are forward-looking statements. Words such as “expects,” “intends,” “plans,” “may,” “could,” “should,” “anticipates,” “likely,” “believes” and words of similar import may identify forward-looking statements. These statements are not historical facts, but instead represent only the Company’s belief regarding future events, many of which, by their nature, are inherently uncertain and outside of the Company’s control. It is possible that the Company’s actual results and financial condition may differ, possibly materially, from the anticipated results and financial condition indicated in these forward-looking statements. Further, information concerning the Company and its business, including factors that potentially could materially affect the Company’s business and financial and other results, are contained in the Company’s filings with the Securities and Exchange Commission, available at www.sec.gov. All forward-looking statements included in this press release are made only as of the date of this press release, and we do not undertake any obligation to publicly update or correct any forward-looking statements to reflect events or circumstances that subsequently occur or of which we hereafter become aware.
Contact Information:
Alexis Quintal
Original Source:
Successful 2022 Milestones Support Value of Gb Sciences’ AI-Enabled Drug Discovery Platform
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QuickBlox’s SDKs and APIs, Q-Consultation Lite allows developers to integrate a virtual meeting room plugin with existing company platforms and websites—like electronic health record systems (EHRs)—in minutes.
LONDON, England, March 7, 2023 (Newswire.com)
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QuickBlox, a cloud-based communication platform provider, today announces the launch of Q-Consultation Lite—an open-source, high-performance video teleconsultation software.
As well as high-quality, secure video calling and instant chat messaging, Q-Consultation Lite provides countless industry-specific use cases with the option to ‘hold’ participants in virtual, real-time queues or waiting rooms before private video appointments. Healthcare professionals, financial advisors, HR recruiters, and other users can leverage this technology for virtual private consultations, coaching, product demos, tutorials, training sessions, and at-home monitoring.
The software is easily integrable with existing company platforms and is a web-and mobile-responsive application compatible with iOS, Android, and the Web. Developers can also modify the software’s code to enhance features such as language, icons, and data capture fields while adapting the user interface to fit the identities and branding of specific companies. And if companies choose to use the free app with the paid QuickBlox HIPAA cloud plan, they would also be HIPAA-compliant with a Business Associate Agreement (BAA).
“Q-Consultation Lite was originally built to meet the extraordinary demand from QuickBlox’s customers for digital and remote communication solutions during COVID-19. After trialing the software with several healthcare organizations, we saw the firsthand benefits, such as reducing the cost of no-show appointments and pressure on clinical resources,” said CEO of QuickBlox, Nate MacLeitch.
He added: “Therefore, while there are many communication solutions on the market, we decided to launch a free, open-source version of our video consultation software to make it accessible to as many people as possible.”
Remote consultation is increasingly used alongside or instead of traditional in-person visits across banking, retail, customer support, and HR industries. Meanwhile, healthcare organizations have discovered the benefits of secure video calling and chat to support psychotherapy, post-surgery care, chronic illness monitoring, wound management, pain management, addiction support, and more.
Some of Q-Consultation Lite’s recent users include a neonatal clinic consulting with parents of at-risk infants, a healthcare organization with an at-home wound management app, and an HR agency looking to use Q-Consultation Lite to manage their recruitment process.
The source code is available via the QuickBlox Github repository, and a fully managed version with additional features is available under a SaaS license. See here for more information.
ABOUT
QuickBlox is a cloud-based communication platform enabling businesses to create real-time communication apps efficiently. With pre-built SDKs and APIs for chat and video calling, ready solutions, and cross-platform compatibility (supporting iOS, Android, Flutter, React Native, and the Web), QuickBlox helps businesses succeed in delivering user experiences comparable to the likes of WhatsApp and Zoom.
Contact Information:
Manuela Villegas
1-646-480-0356
Original Source:
QuickBlox Launches a Free, Open-Source Offering to Make Video Teleconsultation Software Accessible to All
