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CHICAGO – October 24, 2022 – (Newswire.com)…

Gb Sciences’ anxiety formulations were previously identified using the company’s AI-driven PhAROS™ platform, and they have now been evaluated using preclinical zebrafish models of stress at the National Research Council of Canada.

LAS VEGAS – October 24, 2022 – (Newswire.com)

Gb Sciences, Inc. (“GbS”; OTCQB:GBLX), a leading plant-inspired research and biopharmaceutical drug development company, has received positive preclinical results in an interim report from its study using preclinical zebrafish models of stress at the National Research Council of Canada (NRC). GbS’ proprietary anxiety formulations have achieved a statistically significant reduction of stress in this preclinical study. The NRC is testing GbS’ proprietary, psychotropic plant-based formulas for the treatment of depression and anxiety. GbS has leveraged its patent-pending PhAROS™ (Phytomedical Analytics for Research Optimization at Scale) platform to identify these combinations of plant compounds for novel drug candidates. These are the company’s first non-cannabis formulations to advance in preclinical studies.

“We have achieved an important milestone in the development of our novel, kava-inspired anxiety formulations. Not only did some of our formulations achieve statistical significance in the animal model, but these minimum essential mixtures also demonstrated synergy by significantly outperforming the individual active ingredients within our minimum essential mixture formulations,” said Dr. Andrea Small-Howard, Gb Sciences’ President and Chief Science Officer. “This preclinical data also confirms that our PhAROS™ platform was capable of yielding concrete, potentially effective, plant-inspired combination drugs.”

For these novel psychotropic drug candidates, the Gb Sciences research team used the PhAROS™ platform to identify new ingredients to improve upon an initial formulation for anxiety based on traditional medicine. The original plant mixture was derived from the kava plant, but some elements of kava are thought to cause liver toxicity. PhAROS™ identified ingredients from the Piper plant family as a substitute for the functionality of the ingredients in question without the potentially adverse safety profiles of those original ingredients. The Piper plant family includes pepper plants that are used worldwide in traditional medicines.

The PhAROS^TM platform is a revolutionary, AI-driven science gateway and virtual research environment for drug discovery. With its data analytics and machine learning capabilities, PhAROS™ allows Gb Sciences to greatly reduce the time and money required to bring novel, plant-inspired formulations to market. PhAROS™ represents a breakthrough combination of data sciences and traditional plant-based medicines. 

To learn more about Gb Sciences, visit www.gbsciences.com.

About Gb Sciences and GbS Global Biopharma

Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented, disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary, GbS Global Biopharma, Inc. The ‘plant-inspired’ active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences’ intellectual property portfolio contains six issued U.S. and three issued foreign patents, as well as 17 U.S. and 51 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences’ lead program for Parkinson’s disease is being prepared for a first-in-human clinical trial. Gb Sciences’ formulations for chronic pain, anxiety, and depression are currently in preclinical animal studies with researchers at the National Research Council of Canada (NRC). The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences’ productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com. 

Forward-Looking Statements

This press release may contain statements relating to future results or events, which are forward-looking statements. Words such as “expects,” “intends,” “plans,” “may,” “could,” “should,” “anticipates,” “likely,” “believes” and words of similar import may identify forward-looking statements. These statements are not historical facts, but instead represent only the Company’s belief regarding future events, many of which, by their nature, are inherently uncertain and outside of the Company’s control. It is possible that the Company’s actual results and financial condition may differ, possibly materially, from the anticipated results and financial condition indicated in these forward-looking statements. Further, information concerning the Company and its business, including factors that potentially could materially affect the Company’s business and financial and other results, are contained in the Company’s filings with the Securities and Exchange Commission, available at www.sec.gov. All forward-looking statements included in this press release are made only as of the date of this press release, and we do not undertake any obligation to publicly update or correct any forward-looking statements to reflect events or circumstances that subsequently occur or of which we hereafter become aware.

Media Contact

Alexis Quintal

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Madeleine Moench

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Gb Sciences’ Plant-based Formulations Designed to Treat Anxiety Achieve Statistical Significance in Animal Study

LONDON – October 24, 2022 – (Newswire.com)

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Making Raving Fans Hospitality Group, the parent company of Baton Rouge restaurants Jubans Restaurant, SoLou, Portobello’s Grill, and P-Beau’s, promoted Meg Daigle to be the company’s new Vice President of Operations

BATON ROUGE, La. – October 21, 2022 – (Newswire.com)

Making Raving Fans Hospitality Group, the parent company of Baton Rouge restaurants Jubans Restaurant, SoLou, Portobello’s Grill, and P-Beau’s, promoted Meg Daigle to be the company’s new Vice President of Operations. Daigle’s promotion will provide owners Peter Sclafani, Kiva Guidroz, and Michael Boudreaux more time to focus on more business development, including establishing new restaurant concepts and expanding current Making Raving Fans concepts.

Daigle started her career with Portobello’s Grill, one of the Making Raving Fans restaurant concepts, 26 years ago as a college student when she worked as a server before the restaurant relocated away from its Lee Dr. location in Baton Rouge. After graduating from LSU, Daigle moved on to New Orleans as Director of Operations for Raising Cane’s in the early 2000s as the chain was first beginning its rapid expansion. She then went on to hone her full-service skills as part of the team that relaunched Commander’s Palace in New Orleans after Hurricane Katrina.

Daigle returned to Making Raving Fans in Baton Rouge in late 2021, rejoining as Director of People, Culture, and Training, and has since proven herself as a leader within the company. Under Daigle’s leadership, Making Raving Fans has consistently hired top-tier talent even as the hospitality industry faces continued hiring challenges, and she has headed up several initiatives to improve training and company culture.

“During my time in New Orleans, I learned a lot about how to run restaurants efficiently and how to scale operations, and a lot of those skills translate to the type of business model that Making Raving Fans operates under,” said Daigle. “When I saw an opportunity to come back home to Baton Rouge and work with the Making Raving Fans team and help them continue their growth, I didn’t hesitate to reach out.”

Daigle’s recent promotion to Vice President of Operations will allow her to continue to impact the company’s culture while leading the Director of Operations, Director of Culinary, and 41 store-level managers.

“Meg has been phenomenal in leading operations and ensuring that our customers have the best dining experience at all of our restaurants,” said Peter Sclafani, co-owner of Making Raving Fans Hospitality Group. “With her as our first-ever Vice President, Kiva, Michael and I will have more time to focus on continuing to grow our business with the confidence that Meg is able to uphold the current operations. We’re looking forward to expanding the SoLou brand along the I-10 corridor and exploring new concepts as well.”

Making Raving Fans Hospitality was created in 2020 but was initially comprised of restaurants that have been serving high-quality food and drink in the Baton Rouge area for many years. The hospitality group was formed when Chef Peter Sclafani and Kiva Guidroz came together as partners, bringing their decades of experience under one name. Michael Boudreaux later joined the group in 2021, and the team has since added new establishments to its growing portfolio of restaurants. Together, the team continues to push the envelope of Baton Rouge’s culinary culture.

For more information on Making Raving Fans Hospitality Group and its four restaurant concepts, visit makingravingfans.com.

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Contact Information:

Peter Sclafani

Restaurateur, Chef, Consultant, Author

[email protected]

225-938-0019

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Making Raving Fans Hospitality Group Promotes Meg Daigle to Vice President as Company Continues Expansion

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